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Future research endeavors should encompass a comprehensive investigation spanning from preclinical studies to clinical trials

Novel formulations and modes of application include extended-release (ER) oral levodopa (IPX203), levodopa powder for inhalation, and levodopa infusion therapies through subcutaneous (foslevodopa/foscarbidopa, ND0612) or intrajejunal pumps (levodopa [entacapone] carbidopa intestinal gel)

While the body produces glutathione on its own, levels can decline due to factors such as aging, stress, poor diet, pollution exposure, and certain health conditions

To bypass this impenetrable barrier, the cell relies entirely on a three-step biochemical pathway known in medical literature as the carnitine shuttle

10.1038/nrendo.2015.128 Nat