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J Pest Sci

In: Lombardini J.B., Schaffer S.W., Azuma J., editors

As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5

When both glomerular and tubule lesion occur urine insulin excretion increase (Rabkin et al., 1984)

Johnson, Stacey Boyd, Daniel Alvarez-Castegnaro, Solmaz Eskandari Nezhad, Alex Barclay, Kinza Noor, Yao Akpamagbo, Dr