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61 The intracerebroventricular (ICV) administration of STZ elicits a distinct influence on the central nervous system (CNS) without noticeable effects on peripheral regions

To sum up, we summarized the extensive evidence for the beneficial effects of SFN, extending from in vitro studies, to animal models, to various clinical studies

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Forkhead/winged helix transcription factor (Foxp3), the forkhead gene for transcription factors, primarily regulates Treg cell progression (Fontenot et al., 2003)