It violates the spirit of sport (this definition is outlined in the Code)
Based on Phase 2 trial data (Jastreboff et al., NEJM , 2023), the most commonly reported adverse effects of retatrutide include: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (most frequent, particularly during dose escalation) Injection site reactions: Redness, bruising, or mild discomfort Decreased appetite: Generally considered a therapeutic effect but can contribute to nutritional deficiency if severe Increased heart rate: Observed with glucagon receptor agonism
Create before-and-after comparisons easily
It is geared more toward users who are focused on sustained weight loss, rather than those looking to shed pounds for a short-term goal, such as an upcoming event
Exendin-4, a GLP-1 receptor agonist, suppresses diabetic retinopathy in vivo and in vitro
Participants received once-weekly injections of retatrutide at either the 9mg or 12mg dose, or a placebo, over 68 weeks