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These effects diminish the metabolic flexibility and effector functions of immune cells (e.g., macrophages and T cells), making them more susceptible to dysfunction and intensifying immune damage during chronic inflammation [90] (Refer to Supplementary Table 1 for details)

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Real-world persistence data will be particularly important to guide efforts for shoring up the chronic market opportunity, e.g., via digital health support programmes, such as the Omada Health-Evernorth partnership [8]

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Liposomal delivery provides a proven path to restore these levels where standard oral options fail