One trial tested a modified ketogenic gluten-free diet with the addition of MCT supplement and found certain improvements on core autism symptoms except for restricted and repetitive behaviors ( Upon observing that the GF/CF diet resulted in greater improvements in children with ASD who had gastrointestinal symptoms, food allergies, and food sensitivities, Pennesi and Klein ( Gut-Immune-Endocrine-Brain Axis Model for Autism Throughout the years, external agents have been implicated in ASD and investigated mainly via comparisons of their levels in the body systems of or utilization by individuals with ASD and general population, such as pesticides ( With such a paradigm shift in neuroscience ( Though much speculation and theoretical perspectives have been offered about the involvement of the gut-brain axis in ASD in the past decade, recently emerging causal evidence is what brings a more solid grounding to this approach

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