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The retarded leaching of nanoclusters can be attributed to their large size in comparison with molecular dyes and it is a clear advantage for imaging purposes as dye leaching decreases the fluorescence brightness of NPs and increases the background signal resulting in unfavorable imaging inefficiency/artifacts 50

Pigmentation, dullness and uneven tone often involve inflammation, sun exposure, barrier disruption and slowed renewal

The next experimental step included extracting total RNA from the cells through the use of the acid guanidinium thiocyanate-phenol-chloroform extraction method

Most human research was conducted during the 1980s or early 1990s