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Community reports and practitioner protocols converge on the same structure: 2 to 4 weeks on, 2 weeks off

The copper coordination chemistry of GHK-Cu enables controlled cellular delivery of bioavailable copper while simultaneously modulating gene expression patterns, making it a unique multifunctional signaling complex rather than a simple metal chelator

Crane JD, MacNeil LG, Tarnopolsky MA

Am J Gastroenterol (2012) 107:17556

For widespread skin conditions (psoriasis, systemic dermatitis), subcutaneous injection at 200 to 500 mcg/day may be more effective than topical alone

Antioxidant status and lipoprotein peroxidation in chronic fatigue syndrome