Hormone replacement therapy can provide relief for many menopausal issues in the short term but is not suitable for all women
During follow-up visits, the medical team reviews weight trends, hunger signals, and lifestyle factors to ensure that the chosen medication remains the best fit
These medications have been extensively studied in large-scale clinical trials and are licensed by the MHRA for specific indications including type 2 diabetes and, in some cases, weight management, as outlined in NICE guidance (NG28)
doi:10.7759/cureus.31425
Therefore, any relationship between GLP-1 therapy and muscle cramps is more likely to be indirect, mediated through secondary metabolic, nutritional, or fluid balance alterations rather than through direct receptor-mediated effects on muscle tissue
Source : Aly HA, El-Beshbishy HA, Banjar ZM