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Surgical resection can cause direct alterations within the TME that ultimately leads to a number of unfavorable changes including an increase in the number of cancer cells which circulate in the blood and suppression of anti-tumor immunity (Tohme et al., 2017b)

GHK-Cu provides the structural copper needed to cross-link the collagen those cells produce

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A key factor in the experimental protocol is the use of Matrigel as an ECM scaffold, because of its heterogeneity and its poorly defined composition

This matters more for vials you keep for the full 28-day window

Beyond this threshold, nasal absorption becomes increasingly unreliable due to physical limitations in transmucosal permeation