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As TGs accumulate in the circulation after tyloxapol injection, these experiments were terminal, and mice were sacrificed after the 3-hour time point

Why GLP-1 Side Effects Often Start in the Gut The most common side effects reported by GLP-1 users are gastrointestinal: constipation from slowed transit, bloating from altered fermentation patterns, and general discomfort from microbial imbalance

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The corresponding study was published in The Lancet Psychiatry