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00:21:05 Steve Small: Right

Annals of the New York Academy of Sciences, 2004

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Losing muscle reduces your metabolic rate, accelerates plateau formation, and makes any reset period less effective because you are fighting against a slower metabolism

These effects of Pycnogenol on joints can be explained by previous findings, showing that regular intake of Pycnogenol leads to a potent decrease of pro-inflammatory markers like NF-B and COX-enzymes, as well as a decline in the release of matrix metallopeptidase (MMP) enzymes, that are responsible for destroying cartilage in joints (71)

A longer delay may warrant resetting your schedule to a new day that works better for your routine, rather than forcing yourself back to an inconvenient original date