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GH binding to GHR results in activation of JAK2, which subsequently phosphorylates multiple tyrosine residues on the ICD of the receptor (Figure 2) (6, 7)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 107.de Moreno de Leblanc A., LeBlanc J.G., Perdigon G., Miyoshi A., Langella P., Azevedo V., Sesma F

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