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Yes, but more specifically, its hair shedding

Tirzepatide is a dual GIP/GLP-1 receptor agonist , meaning it activates two gut hormone receptors that help regulate appetite, digestion, and blood sugar

To increase aqueous solubility of the compounds to facilitate structural studies, the cycloheptyl substituent in TGR uncompetitive inhibitor 8 was replaced with a sugar moiety, resulting in compound 9 , a noncompetitive inhibitor and thus capable of binding the enzyme in absence of NADPH

Porter D, Faivre E, Flatt PR, et al

These findings remain consistent with the established safety profile of the GLP-1 class.