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doi: 10.1016/S0272-6386(12)80667-6 292
Incretin-based drugs are now being investigated and in some cases approved for a wide range of conditions, including cardiovascular disease, chronic kidney disease, sleep apnea, fatty liver disease (MASLD), neurodegenerative disorders, and even substance-use disorders
This is precisely the mindset we aim to foster
But anyway that's sort of my hypothesis, which is I don't actually know what's causing Alzheimer's disease, I don't know how to treat it, I don't know if it's treatable once it's in a late enough stage, but I firmly believe that if you can be as insulin-sensitive as possible, for you as an individual you reduce your risk
Eli Lillys FDA approval announcement on 1 April 2026 described Foundayo as the only GLP-1 pill for weight loss that can be taken without food or water restrictions, a formulation milestone that Lilly has described as removing a practical barrier which has complicated adherence to earlier oral GLP-1 options