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In addition, consistent with the findings reported elsewhere, we found DMF induces the activation of NRF2, and NRF2 targets such as those involved in cystine uptake (SLC7A11) and GSH biosynthesis (GCLM and GCLC, the mediator and catalytic subunits of GCL) (Fig

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At the end of the study, it was suggested that CJC-1295 contributed to a 7.5-fold increase in the growth hormone pulsatility levels as compared to that of the placebo

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In vivo study showed that UA can induce autophagy, the primary process for clearing intraneuronal aggregated -synuclein, by inhibiting mTOR/ULK1 signaling in the midbrain of SNCA A53T transgenic mice

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