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This problem was resolved by transwell models comprising co-cultures with other cell types (Hurwitz et al., 1993)

Berberine, a plant-derived alkaloid, works primarily by activating AMP-activated protein kinase (AMPK), influencing glucose and lipid metabolism

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Mitochondrial autophagy in the sleeping brain

Additionally, supplementing GlyNAC was also closely associated with the hallmarks of aging, including mitochondrial dysfunction, mitochondrial biogenesis, intercellular communication, nutrient sensing, loss of proteostasis, stem-cell exhaustion, genomic damage, cellular senescence, and telomere attrition

It has a good and linear correlation with the hyperinsulinemic-euglycemic clamp method