Loose motions are rare, but are a common reason for not being able to tolerate the drug
However, common microvascular complications such as the threatening diabetic retinopathy (DR) have not only exacerbated the condition of diabetic patients but also significantly reduced their prognosis, and by 2020, the number of people with DR had exceeded 100 million globally, and is still on the rise [1, 2]
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A third ADH1C allele encodes a Thr(T) at position 352 (identified as the ADH1C*Thr352 allele) that has been found in Native American populations but the protein has yet to be fully characterized
Metabolism (2014) 63(1):919
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