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The agency typically issues a final decision four to nine months after the comment period closes, putting an answer somewhere in the November 2026 to March 2027 window

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AMPK activation may facilitate glucose uptake, enhance fatty acid oxidation, and suppress lipogenesis [100]

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Its important to emphasize up front that most of the dosing data for DSIP comes from a research setting, research and anecdotal reports, not formal regulatory guidance or definitive dosing guidelines

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