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Lippincott Williams & Wilkins

Some researchers report stability up to 6-8 weeks under strict sterile conditions, but the conservative recommendation is 4 weeks

For inflammatory bowel disease (IBD) and Crohn's/colitis , evening dosing shows theoretical advantages as nocturnal gut rest periods enhance mucosal healing when inflammation suppression coincides with reduced digestive burden

However, early responders during (those that lost more than 10% of their starting weight by week 16) saw an average weight loss of 22% by the end of the trial

It's also sometimes sold as a supplement, which is popular with bodybuilders and athletes, who believe it may help them to control their body temperature and reduce muscular fatigue during exercise

While this may sound impressive, none of these assertions are based on human trials