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The most impactful upcoming change: if the BALANCE model transitions to permanent Medicare Part D coverage in 2028 as planned, approximately 50 million Medicare beneficiaries will gain access to GLP-1 for obesity treatment

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling

Sources FDA FDA Approves New Medication for Chronic Weight Management FDA Wegovy Prescribing Information New England Journal of Medicine Once-Weekly Semaglutide in Adults with Overweight or Obesity New England Journal of Medicine Tirzepatide Once Weekly for the Treatment of Obesity CDC Adult Obesity Facts NIDDK Definition & Facts for Adult Overweight & Obesity World Health Organization Obesity: GLP-1 Therapies