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In research settings, it is commonly used: As a diluent or vehicle for certain compatible research compounds For reconstitution of lyophilized materials in non-clinical experiments In applications that may require multiple withdrawals from the same container when aseptic procedures are followed The 30mL container format offers convenient volume for repeated use in small to moderate-scale experiments, providing flexibility for ongoing or multi-step protocols

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The ROSE/TRIO-12 was a randomized, placebo-controlled, phase III trial evaluating the addition of ramucirumab to first-line docetaxel treatment in HER2-negative metastatic breast cancer (Mackey et al., 2015)