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Independent validation of protein changes in energy metabolism and the antioxidant system was carried out by Western blotting and showed sex-related differences

Stage 5: Regulatory Submission and Stability Monitoring Data generated from PPQ batch release testing, together with accelerated and long-term stability studies, are compiled into the relevant CTD Module 3 regulatory documentation

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Consistently, the livers of HFD-fed mice showed increased IKK--SSG levels, decreased IKK- phosphorylation, and suppressed NF-B activation when compared to these from control animals

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