Medications: Some medications, such as hormone replacement therapy, chemotherapy and certain antibiotics, can increase sensitivity to sunlight and cause pigmentation as a side effect
Imaging Biomarkers Several imaging techniques such as magnetic resonance imaging (MRI), transcranial sonography (TCS), single-photon emission computed tomography (SPECT), and positron emission tomography (PET) have been used to identify structural changes in the substantia nigra
Sleep issues are often secondary to something else, including brain-based issues, and it may take some sleuthing to find the source
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TB-500 and Neurological Recovery Research In a rat embolic stroke model, administration of T4 at 24 hours after middle cerebral artery occlusion and every 3 days for 4 additional doses produced significant improvement in functional neurological outcome with evidence of axonal remodelling at the ischaemic boundary, increased oligodendrocyte precursor cells in the SVZ, striatum, and corpus callosum, and increased mature oligodendrocytes suggesting a mechanism involving axonal remodelling rather than direct neuroprotection
Combinations of antiretroviral drugs administered as highly active antiretroviral therapy (HAART) reduced the AIDS mortality