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Other lipid-lowering drugs include colesevelam, fibrates, nicotinic acid, and ezetimibe

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Retatrutyd jest badany w kilku obszarach: otyo i nadwaga (program TRIUMPH), cukrzyca typu 2 (TRANSCEND), metaboliczna stuszczeniowa choroba wtroby (MASLD/NAFLD) oraz zesp metaboliczny

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It is therefore noteworthy that GAN DIO-NASH-HCC mice showed spontaneous and progressive hepatic tumor development with clear histological features of HCC, lending further support to clinical translatability of the model

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In acid sphingomyelinase knock-out mice, which mimic a neurovisceral acid sphingomyelinase deficiency (ASMD) characterized by cellular accumulation of sphingomyelin, the effects of a choline-free diet decreased the activation of liver macrophages and microglia, but it did not significantly alter sphingomyelin levels due to compensatory mechanisms involving methionine metabolism (101)

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Comp Clin Pathol 28 , 17511759 (2019)

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