The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting
Individuals taking blood thinners, diabetes medications, or cholesterol-lowering drugs (statins) should speak with their healthcare provider before use
Exposure to heat or sunlight may lead to melting/damage of product
Dose equivalence considerations The tirzepatide conversion chart helps when switching between different concentrations or formulations
[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Shaito A, Aramouni K, Assaf R, et al
Responses to the open-ended question were analyzed using thematic analysis