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Here's how your morning habits may support natural GLP-1 function: Circadian rhythm alignment: Consistent wake times and morning light exposure help synchronize your circadian rhythm, which regulates glucose metabolism, insulin sensitivity, appetite hormones, and energy expenditure
The observed protective association between GLP1-RAs and PI in the context of glycated hemoglobin lowering may be due to the efficacy of GLP-1RAs in lowering blood glucose, which could mitigate hyperglycemic mesenteric microvascular damage and therefore improve blood flow to the ileum [31], reducing the risk for PI
In 2024, there were 8.4 million prescriptions and $8.6 billion in spending on GLP-1s in Medicaid, and 21.8 million claims and $27.5 billion in gross spending (not excluding rebates) on GLP-1s in Medicare (Figure 1)
Maintaining digestive health long-term requires continued attention to the fundamentals
They are most effective for mild constipation
Ask your doctor about ways to monitor this, including through body-composition testing
