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Rivadeneira et al

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Instead, similar to the C-reactive protein, which is still regarded as useful in monitoring the pathological status of immune-related conditions (for example, rheumatoid arthritis), we propose that GSH can be used as a candidate objective marker for mental disorders, in combination with other markers

Biochemical analysis Serum urea and creatinine levels While the serum urea level of the MTX group significantly decreased, the serum creatinine level significantly increased compared with the control group (Table 2)

Hydrogen peroxide (H2O2) and reduced glutathione can react without catalysis of GSH-Px, so the portion of GSH reduction by non-enzymatic reaction should be subtracted