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On top of that, he suffered from a heart attack, a liver condition, and diabetic neuropathy, which damages nerves and causes numbness and weakness in the hands and feet

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TKT, as part of the cytosolic pentose phosphate pathway, along with the mitochondrial multienzyme complexes of pyruvate (PDHC) and 2-oxoglutarate dehydrogenases (OGDHC), are essential for energy production from glucose oxidation

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