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Cysteine catabolism for mitochondrial energy production A recent study revealed that mitochondrial sulfur metabolism makes an important contribution to the cellular energy production (Akaike et al

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Evans and Masullo, 2023

Specific ferroptosis inhibitors like Ferrostatin-1 can effectively block lipid peroxidation but suffer from poor metabolic stability in vivo , low bioavailability, and potential off-target effects (112)

Rat full-thickness wounds (6mm diameter, 13-day study) treated with GHK showed 64.5% reduction in wound size compared to 45.6% for vehicle-treated and 28.2% for control group, accompanied by significantly lower TNF- and elastin-degrading MMPs