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Measurable improvement in skin firmness and elasticity Deeper wrinkles appearing less pronounced Facial contours appearing more defined Acne scarring and depressed scars visibly improving Skin density and plumpness noticeably increased The most significant and compelling before-and-after changes occur in this window

Some practitioners run continuous protocols, but cycling remains the conservative approach until more long-term data exists

This positions FOXO4-DRI within advanced molecular longevity research rather than endocrine or metabolic peptide categories

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