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When mutating the second cysteine of the C 21 C 22 LC 24 motif to serine, only the band that corresponds to the C21-C24 disulfide was formed (Fig

In the central nervous system, oligodendrocytes (OLs) are a particularly specialized type of glial cell which provide fundamental support to neuronal activity by producing the myelin sheath (van Tilborg et al., 2016

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This is not a reason to start metformin on its own, but it is a relevant consideration if metformin is already part of the clinical conversation

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