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History of Medullary Thyroid Carcinoma (MTC) or MEN 2 Individuals with a history of medullary thyroid carcinoma (a type of thyroid cancer) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid semaglutide due to the potential risk of worsening these conditions

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The excess release of parathyroid hormone (PTH) can lead to over resorption of renal calcium leading to hypercalcemia

signs of an allergy may include rash, hives, itching, or even anaphylaxis (a severe allergic response) in highly sensitive individuals

Areas with miniaturized follicles still producing vellus hair may respond to treatment