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Design of engineered GLP-1 albumin fusions with favorable FcRn binding properties The FDA-approved GLP-1 RA, Tanzeum (albiglutide), consists of two repeats of the DDP-4-resistant GLP-1 (residues 736) peptide fused in tandem to the N-terminal end of human albumin (Fig
In these experiments, rates of release are expressed as % of contents unless otherwise indicated
Semaglutide ( n = 4, SUSTAIN-6 [14], PIONEER-6 [15], SELECT [8], SOUL [16])
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They can include: Injection site reactions: Temporary discomfort, bruising, or inflammation where the IV is placed
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Lei et al., 2015
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