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Science objectives [edit] The Juice orbiter will perform detailed investigations on Ganymede and evaluate its potential to support life

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337 Concurrently, age-related decreases in PINK1/Parkin-mediated mitophagy promote oxidative stress and mitochondrial dysfunction, which can trigger synovial inflammation and reduce the osteoclast activity critical for healthy bone remodeling, thereby contributing to joint damage and motor impairment

Glutathione and Immune Function Glutathione may support immune cell function in several ways