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Assays performed with leaf extracts of these lines indicated that GSAAT(C138S) and GSAAT(C396) are weakly stimulated by the addition of DTT (by up to 20% compared to their UT samples)

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Additionally, its abundance is reduced in patients with various diseases, such as IBD 76 , colorectal cancer 77 , and chronic kidney disease 78

and Escherichia coli to enhance their ability to inhibit host protein synthesis 341

For others, the effects are more gradual

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