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A 2018 systematic review and meta-analysis identified 20 randomized controlled trials (published between 2007 and 2017) that examined the effect of supplemental lipoic acid on markers of glucose utilization in 1,245 subjects with metabolic disorders (not limited to type 2 diabetes) (60)

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The strongest association appeared among participants who reported drinking at least five cups a day

SREBP1 is also involved in the regulation of the pentose phosphate pathway

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Establishment of 143B subcutaneous osteosarcoma mouse model and therapeutic effect evaluation Tumor model establishment and biodistribution study of NP4 in vivo Three female BALB/c nude mice were subcutaneously inoculated with 143B human osteosarcoma cells (3 10 6 ) on the right buttock