McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM, Hawker GA, Henrotin Y, Hunter DJ, Kawaguchi H, Kwoh K, Lohmander S, Rannou F, Roos EM, Underwood M (2014) OARSI guidelines for the non-surgical management of knee osteoarthritis
(Wilding JPH et al., NEJM 2021) The SELECT trial (N=17,604), published in the New England Journal of Medicine in 2023, showed a 20% reduction in major adverse cardiovascular events (MACE) with semaglutide 2.4 mg in adults with existing cardiovascular disease and overweight or obesity but without diabetes (Lincoff AM et al., NEJM 2023)
The synthetic form of exendin-4, known as exenatide , became the first GLP-1 receptor agonist licensed for clinical use in the EU in 2006
Polydatin treatment alleviates tubular cell apoptosis and rescues renal function in sepsis-induced AKI (Gao et al., 2020b)
A few require medical attention
This process is also important not just for athletes, but also to anyone wanting to support general health, enhance energy, or boost heart performance
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