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The bait protein is usually fused with a tag, such as polyhistidine (His), glutathione-S-transferase (GS) biotin tag captured by Glutathione-, nickel chelate or monomeric avidin magnetic beads, respectively

Strikingly, untargeted metabolomics also revealed significantly elevated hepatic levels of seven standard amino acids in Gpr146 / mice, namely histidine, cysteine, lysine, valine, leucine, isoleucine, and phenylalanine (Supplementary Fig

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130 In addition to preventing a stress-induced inflammatory response, an essential oil extract of perilla prevented depression-related behaviors in chronically stressed mice