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The proposed revisions would weaken several monitoring and containment requirements that were originally implemented after years of litigation and community complaints involving cancer risks tied to ethylene oxide exposure

doi: 10.1371/journal.pone.0025269

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This can lead to underdosing (reduced effectiveness) or overdosing (increased side effects)

Fujimoto WY (2000) The importance of insulin resistance in the pathogenesis of type 2 diabetes mellitus