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The Centers for Medicare and Medicaid Services said it has informed insurers that provide Medicare Part D drug plans that they could cover the medication after the FDA expanded the approval this month

52 In a phase 1, randomized, double-blind placebo-controlled trial in individuals with obesity (without diabetes), this drug resulted in weight loss of 15% over 12 weeks at its highest dose of 420 mg (Table 2)

In Phase 2 trials, participants achieved an average weight loss of 24.2% of their body weight over 48 weeks

5 Additional considerations include patients renal function, other comorbidities, planning pregnancy, cost and coverage, ease of administration, and patient preference

They also calm inflammation , a hidden trigger for many chronic illnesses, including heart disease, fatty liver, and metabolic syndrome

Among the main producing countries, Thailand has over 200 durian varieties, with 60-80 being primarily cultivated