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Although, in general, patients who are heterozygous for SLC22A5 mutations have been thought to be asymptomatic, Garavaglia et al

Unlike temporary hair shedding, male pattern baldness is permanent

123 L-Cys and water can further react to generate H 2 S

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These data are consistent with alanine substitution of TMD residues lining the binding cavity generally having limited impact on exendin-P5 affinity, suggesting its affinity is largely driven by interactions with the ECD (Figures 4-5, Supplemental Figure 9)