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The approval was based on the OASIS clinical trial programme and the SELECT cardiovascular outcomes trial, with the OASIS 4 study showing a mean weight loss of 16.6% at 64 weeks in adults with obesity or overweight, among participants who adhered to treatment

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the buzz stayed steady, a hum of vitality that took me through the rest of the day and into the evening until I powered down with ease, slipping into slumber like a lion with a belly full of prey