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Animal-to-human amount translation is not straightforward and requires allometric scaling, and human pharmacokinetics, safety, and efficacy remain uncharacterized in published literature

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Table 4 offers instructive examples from preclinical studies for improving nanoparticle efficiency, including size, surface modifications, and biocompatibility

To calculate the dose, use the formula: Units = (Dose in mg Concentration in mg/mL) 100

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