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Through weight loss, most of these medications are beneficial for heart disease, but there are some special considerations for certain drugs. Heart health benefits of GLP-1 agonists in people without diabetes Recent studies have shown that GLP-1 agonists might also reduce the risk of cardiovascular disease

For comparison, semaglutide at its 2.4 mg dose produced an average weight loss of 15.0% , with 34% of participants hitting that 20% loss milestone