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Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes

Example of linker cleaved by cathepsin B Figure 6

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To assess the ability of GSH and GSS to discriminate between amyloid PET-positive and -negative individuals, receiver operating characteristic (ROC) curve analysis was performed using models based on biomarker concentrations alone, and in combination with age, sex, and APOE 4 carrier status