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Mechanism of Action of IGF-1 LR3 IGF-1 LR3 binds to the IGF-1 receptor (IGF1R) , activating intracellular pathways such as: PI3K/Akt/mTOR pathway Drives protein synthesis and muscle growth MAPK pathway Influences cell proliferation and differentiation Key effects include: Stimulating muscle stem cells (satellite cells) Increasing nitrogen retention in muscle tissue Enhancing glucose uptake for energy and glycogen replenishment Promoting connective tissue healing 6

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Naturally occurring copper-binding peptide

A cell-culture result does not establish longer life, delayed ageing or clinical safety in people

Epub 2007 Jun 18

Structure determination and refinement of human class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes