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To increase the targeting specificity of such therapeutics, senotherapeutic agents are integrated with nanoparticle-based delivery systems to achieve precise intervention in senescent cells

DT40 cellsfrom KJ Patels laboratory stockwere grown in RPMI medium supplemented with 3 % chicken serum (Gibco, # 16010167), 7 % Fetal calf serum (Gibco, # 16110082), 50 mol L 1 -mercaptoethanol, and P/S 11

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