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Animal experiments The adult female Sprague-Dawley (SD) rats (about 160 g, 6 weeks old), SD juvenile rats (50100 g, about 24 weeks old) and SD neonatal rats (2040 g, about 12 weeks old) used in the experiment were purchased from the Laboratory Animal Center of Army Medical University

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With age, NAD+ levels naturally decline, leading to a decrease in cellular function and vitality