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SKU: 93877175422

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Description

Cell Tissue Res

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Defective p53 activity is increasingly implicated in the etiology of several additional uncommon genetic disorders, such as DiamondBlackfan anemia (DBA), CHARGE syndrome, and ATR-Seckel syndrome

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Following the availability of data from these various studies, and data on c-MET expression as a biomarker that indicates a poor prognosis in patients with gastrointestinal cancer and increased c-MET expression, inhibitors targeting this pathway have entered the clinic in the past decade

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